Ethyl Cellulose for pharmaceutical application Ethyl Cellulose for industrial Usage

 

Introduction
Name: Ethyl Cellulose
Abbreviation: EC
Structural formula:In the formula, n stands for degree of polymerization and R for –H or –C2H5.
Characteristics:
Ethyl Cellulose is a kind of white grains or powder, having no smell or tastes. Its 5% soliquoid shows neutral to litmus test paper. Its specific density 1.07~1.18, heat distortion point: 135~155degree centigrade, and fire point: 330~360 degree centigrade. Ethyl Cellulose has good stability against light, heat, oxygen and wetness, and is stable to chemicals. It is resistant to alkali, dilute acid and salting liquid, soluble in some organic solvents, such as alcohol, ether, ketone, ester, aromatic hydrocarbon and halohydrocarbon, etc, and compatible with many celluloses, resin and nearly all plasticizers. Ethyl Cellulose has low combustibility, small hydroscopicity and good electric behavior. Its thin film and plastics have good mechanical strength and flexibility in a wide range of temperature.
Technical requirements:
Ethyl Cellulose conforms to Chinese Pharmacopoeia 2000 edition, American Pharmacopoeia USP24/NF19 standard and European Pharmacopoeia EP4.

1. Appearance:White or even yellowing powder or grains, without any smell or taste.
2. Technical Index
Item

Index

K type

N type

T type

Content of ethoxy, %

44.0~47.9

48.0~49.5

49.6~51.0

Viscosity (ethanol-toluene solvent, weight, ratio)mPas

Conform to the requirements of table 2

Residue on ignition, % <=

0.4

Loss on drying %

3.0

Heavy metal %

0.0020

Arsenic salt %

0.0002
3. Viscosity Specification
Level

Specific range

Level

Specific range

7

5.6~8.4

100

80~120

10

9~11

150

135~165

15

13.5~16.5

200

180~220

20

18~22

250

221~270

30

27~33

300

271~330

50

45~55

 

 

Note: Provided that buyers have other requirements, negotiation might be necessary between Supplier and Buyer.
Usage
Due to its insolubility in water, ethyl cellulose is mainly used as tablet adhesive and thin film coating material, etc. It is also used as retarding agent for aggregate to make various types of aggregate slow-release pills; as slow-release agent or slow-release pills for compound material when making coat; as microcapsule material to make the medical effect release continuously, and avoid the preaction of water soluble medicine. It can be too used in any type of medicine as dispersing agent, stabilizer and water retention agent to prevent medicine from absorption and deterioration, enhance the safe storage and stability of pills. It can even be used as adhesive, slow-release agent and moisture-repellant agent for vitamine pills and mineral pills.
Instruction for usage
While padding, add Ethyl Cellulose slowly into the container with solvent until it is fully wetted and dissolved.
Package
It is packed in paper bags, fiberboard boxes or drums lined with PVC bags. Net weight per package: 10kg/20kg/50kg
Instruction for storage
Seal it and store in dry place.